Honeywell HEPA Replacement Media Filter for CPZ 17250. The Honeywell HEPA 28720 Replacement Media Filter is fully capable of capturing up to a staggering 99.97% of airborne particles as small as 0.3 microns from the air that passes through the filter. This HEPA replacement is the premier defense in reducing airborne allergens such as mites, mold spores, pet dander, smoke and dust. For the very best results, it is recommended that you replace your Honeywell 28720 HEPA Media Filter every 1 to 3 years depending on your indoor environmental conditions. Accept no imitations and achieve the ultimate in peace of mind with this Certified Honeywell Filter. The Honeywell Universal Activated Carbon Pre-Filer features a robust compatibility range that covers the following Air Cleaner Models: F112C, 41200, 61200, 17250, 11200.